doi: 10.1111/j.1471-4159.2006.03742.x 48
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Followingly, the nanoparticles generated from P4 are referred to as NP4 and from P2 as NP2 (Fig
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The matrix, X, of normalized gene abundances with samples on the rows and the biomarker genes on the columns was provided to the opls function of the ropls package with parameters predI = 2 (derive 2 PCA components) and permI = 100 (perform 100 random permutations of the class labels to evaluate predictive performance) to predict the biological condition (Y)